Volume 2 Supplement 1

Metabolism, Diet and Disease 2014: Cancer and metabolism

Meeting abstracts

This supplement has not been supported by sponsorship.

Metabolism, Diet and Disease 2014: Cancer and metabolism. Go to conference site.

Washington DC, USA28-30 May 2014

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Reductive carboxylation mediated oxidative stress defense supports anchorage independent cell growth

Authors: Lei Jiang, Matthew Mitsche, Ralph Deberardinis and Karine Smans

Citation: Cancer & Metabolism 2014 2(Suppl 1):P30

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CRTC1 transcriptional coactivator is required for hepatitis B virus gene expression and replication

Authors: Hei-Man Vincent Tang, Wei-Wei Gao, Chi-Ping Chan, Kin-Hang Kok and Dong-Yan Jin

Citation: Cancer & Metabolism 2014 2(Suppl 1):P31

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A metabolic signature of colon cancer initiating cells

Authors: Christelle Johnson, Kai-Yuan Chen, Xiaojing Liu, Pengcheng Bu, Jason Locasale and Xiling Shen

Citation: Cancer & Metabolism 2014 2(Suppl 1):P32

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Quantifying the demand for central carbon metabolism precursors for biosynthesis in proliferating cells

Authors: Mark Keibler, Thomas Wasylenko, Joanne Kelleher and Gregory Stephanopoulos

Citation: Cancer & Metabolism 2014 2(Suppl 1):P35

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The biochemical mechanism of hypoxia-induced mobilization of glycogen in cultured cancer cell

Authors: Mung Kwan Long and Wong Nai Sum

Citation: Cancer & Metabolism 2014 2(Suppl 1):P37

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The Regulation of TIGAR

Authors: Pearl Lee, Eric C Cheung and Karen H Vousden

Citation: Cancer & Metabolism 2014 2(Suppl 1):P38

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Quantification of NADPH balance during adipogenesis

Authors: Ling Liu, Supriya Shah, Jing Fan, Kathryn Wellen and Joshua Rabinowitz

Citation: Cancer & Metabolism 2014 2(Suppl 1):P40

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LC-MS and GC-MS based metabolomics platform for cancer research

Authors: Wenyun Lu, Sisi Zhang, Xin Teng, Eugene Melamud, Mitchell A Lazar, Eileen White and Joshua D Rabinowitz

Citation: Cancer & Metabolism 2014 2(Suppl 1):P41

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Roles of endocrine FGF signaling in metabolic health and cancer

Authors: Yongde Luo, James Abbruzzese and Wallace McKeehan

Citation: Cancer & Metabolism 2014 2(Suppl 1):P43

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Pancreatic cancers depend on a non-canonical glutamine metabolism pathway

Authors: Costas Lyssiotis, Jaekyoung Son, Joesph Mancias, Haoqiang Ying, Alec Kimmelman and Lewis Cantley

Citation: Cancer & Metabolism 2014 2(Suppl 1):P44

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Associations between diet, gut microbiota and markers of CRC risk

Authors: Tyler Culpepper, Maria Ukhanova, Xiaoyu Wang, Yijun Sun and Volker Mai

Citation: Cancer & Metabolism 2014 2(Suppl 1):P45

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Metabolic transformations in breast cancer subtypes

Authors: Devina Mitra, Stephan Bernhardt, Zita Soons, Gernot Poschet, Ruediger Hell, Rainer Koenig, Ulrike Korf and Stefan Wiemann

Citation: Cancer & Metabolism 2014 2(Suppl 1):P48

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Extracellular lactate cooperates with limited glucose and glutamine to sustain breast cancer cell survival by providing ATP, NADPH, amino acids, and glutathione

Authors: Jennifer Molina, Pietro Morlacchi, Leslie Silva, Jennifer Dennison and Gordon Mills

Citation: Cancer & Metabolism 2014 2(Suppl 1):P49

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Palmitoleate attenuates diet induced insulin resistance and hepatic inflammation independently of PPAR-α

Authors: Camila O Souza, Alexandre A de S Teixeira, Edson A de Lima, Helena A Batatinha, Sandro M Hirabara, William T Festuccia and José Cesar Rosa Neto

Citation: Cancer & Metabolism 2014 2(Suppl 1):P52

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Comprehensive quantitation of metabolite concentrations, gross reaction fluxes, and reaction free energies across cells from four organisms

Authors: Junyoung Park, Sara Rubin, Yi-Fan Xu, Daniel Amador-Noguez, Jing Fan and Joshua Rabinowitz

Citation: Cancer & Metabolism 2014 2(Suppl 1):P54

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Investigating the role of inorganic phosphate in tumor metabolism and metastasis

Authors: Cesar Perez Ramirez and Dorothea Fiedler

Citation: Cancer & Metabolism 2014 2(Suppl 1):P55

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Metabolic mechanisms regulating distinct steps of the melanoma metastatic cascade

Authors: Elena Piskounova, Michalis Agathocleous, Zeping Hu and Sean Morrison

Citation: Cancer & Metabolism 2014 2(Suppl 1):P56

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Pyruvate dehydrogenase activity is required for optimal growth under lipid deficient conditions

Authors: Kartik Rajagopalan and Ralph DeBerardinis

Citation: Cancer & Metabolism 2014 2(Suppl 1):P58

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Mitochondrial complex I modulation targets metabolic plasticity in breast cancer cells

Authors: V Krishnan Ramanujan, Qijin Xu and Eva Biener-Ramanujan

Citation: Cancer & Metabolism 2014 2(Suppl 1):P59

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Metabolic biomarkers for the differential diagnosis of pancreatic ductal adenocarcinoma vs. chronic pancreatitis

Authors: Julia Mayerle, Holger Kalthoff, Regina C Reszka, Beate Kamlage, Erik Peter, Bodo Schniewind, Sandra González-Maldonado, Volker Liebenberg, Christian Pilarsky, Philipp Schatz, Jonas A Schreiber, Ulrich F Weiss and Robert Grützmann

Citation: Cancer & Metabolism 2014 2(Suppl 1):P60

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Troglitazone suppresses tumor cell growth and glutamine metabolism through a PPAR-independent mechanism

Authors: Miriam Reynolds and Brian Clem

Citation: Cancer & Metabolism 2014 2(Suppl 1):P61

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Oncogenic signaling upstream of mTORC1 drives lipogenesis and proliferation through SREBP

Authors: Stéphane Ricoult, Jessica Yecies and Brendan Manning

Citation: Cancer & Metabolism 2014 2(Suppl 1):P62

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Mitochondria, metabolism and cancer: a growing role in cancer cell differentiation and cancer cell dormancy

Authors: Roberto Scatena, Patrizia Bottoni and Bruno Giardina

Citation: Cancer & Metabolism 2014 2(Suppl 1):P64

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Resveratrol differentially regulates NAMPT and SIRT1 in hepatocarcinoma cells and primary human hepatocytes

Authors: Susanne Schuster, Melanie Penke, Theresa Gorski, Anja Barnikol-Oettler, Rolf Gebhardt, Wieland Kiess and Antje Garten

Citation: Cancer & Metabolism 2014 2(Suppl 1):P65

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Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer

Authors: Ayesha Shajahan-Haq, Katherine Cook, Jessica Schwartz-Roberts, Ahreej Eltayeb, Diane Demas, Anni Warri, Leena Hilakivi-Clarke and Robert Clarke

Citation: Cancer & Metabolism 2014 2(Suppl 1):P66

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Identifying metabolomic features that predict metastasis of melanoma from a primary site

Authors: Xiaolei Shi, Zeping Hu, Elena Piskounova, Michalis Agathocleous, Sean Morrison and Ralph DeBerardinis

Citation: Cancer & Metabolism 2014 2(Suppl 1):P67

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Characterization of the different S6Ks isoforms interacting partners

Authors: Isadora Pavan, Flávia Ferreira, Lidia de Freitas, Mariana Tavares, Camila do Amaral and Fernando Simabuco

Citation: Cancer & Metabolism 2014 2(Suppl 1):P68

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A role for central carbon metabolism in mammalian embryonic development?

Authors: Marteinn Snaebjornsson, Nicole Prior, Vinay Bulusu, Bernd Simon, Teresa Carlomagno and Alexander Aulehla

Citation: Cancer & Metabolism 2014 2(Suppl 1):P69

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Catechin-rich green tea extract increases the expression of genes of the cholesterol synthetic pathways in livers of normal diet- and high-fat diet-fed rats

Authors: Toshikazu Suzuki, Mayumi Nagata and Ayumi Takagi

Citation: Cancer & Metabolism 2014 2(Suppl 1):P71

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Long-term hospitalized elderly people have lowered L-carnitine and coenzyme Q₁₀ in blood than healthy elderly people

Authors: Michiyo Takahashi, Toshikazu Suzuki, Hikaru Matsumoto, Hitoshi Nukada and Naotaka Hashizume

Citation: Cancer & Metabolism 2014 2(Suppl 1):P72

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Short treatment of metformin attenuated insulin resistance and hepatic steatosis in obese mice by mechanisms independents of PPAR-alpha

Authors: Alexandre Teixeira, Camila Souza, Edson Lima, Helena Batatinha and José Rosa Neto

Citation: Cancer & Metabolism 2014 2(Suppl 1):P73

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The kinase domain of PFKFB4 is required to stimulate the glucose metabolism and growth of H460 xenografts

Authors: J Clark, Y Imbert-Fernandez, J Chesney and S Telang

Citation: Cancer & Metabolism 2014 2(Suppl 1):P74

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Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate and promotes histone methylation

Authors: Jing Fan, Xin Teng, Ling Liu, Ryan Looper and Joshua Rabinowitz

Citation: Cancer & Metabolism 2014 2(Suppl 1):P75

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Disruption of the endocannabinoid system is prominent in lung adenocarcinoma and associated with poor patient survival

Authors: Kelsie Thu, Roland Hubaux, Stephen Lam and Wan Lam

Citation: Cancer & Metabolism 2014 2(Suppl 1):P76

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Pioglitazone and thyroid cancer risk in patients with type 2 diabetes

Authors: Chin-Hsiao Tseng

Citation: Cancer & Metabolism 2014 2(Suppl 1):P77

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Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition

Authors: Danielle Ulanet, Abhishek Jha, Kiley Couto, Sung Choe, Amanda Wang, Hin-Koon Woo, Mya Steadman, Byron DeLaBarre, Stefan Gross, Edward Driggers, Marion Dorsch and Jonathan Hurov

Citation: Cancer & Metabolism 2014 2(Suppl 1):P78

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The NADP⁺-dependent IDH1 mutation and its relevance for glioblastoma patient survival

Authors: Cornelis JF Van Noorden

Citation: Cancer & Metabolism 2014 2(Suppl 1):P79

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Cell proliferation and tissue remodeling are major determinants of cancer metabolism and the response to drugs targeting metabolism

Authors: Elke Markert, Philip Tedeschi, Sonia Dolphi, Kim Hirshfield, Joseph Bertino, Zoltan Oltvai and Alexei Vazquez

Citation: Cancer & Metabolism 2014 2(Suppl 1):P80

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The power of natural phenolic compounds: caffeic acid is able to enhance the retinoid-induced differentiation of tumor cells

Authors: Renata Veselska, Petr Chlapek, Miroslava Krzyzankova, Silvia Chovanova, Jakub Neradil, Karel Zitterbart and Jaroslav Sterba

Citation: Cancer & Metabolism 2014 2(Suppl 1):P81

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Lung tumors and non-malignant airways from patients with chronic lung inflammatory disease bear distinct genetic and epigenetic disruptions corresponding to metabolic processes involved in senescence and methylation

Authors: Emily Vucic, Kelsie Thu, Victor Martinez, Chiara Pastrello, John Yee, Igor Jurisica, Stephen Lam and Wan Lam

Citation: Cancer & Metabolism 2014 2(Suppl 1):P82

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Glycine decarboxylase is a target for transcriptional repressor Snail

Authors: Guohua Chen, Stephanie Lucas and Jian Wang

Citation: Cancer & Metabolism 2014 2(Suppl 1):P83

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Metformin down-regulates epithelial-mesenchymal transition (EMT) in fibroblasts from burned patients

Authors: Michael Wetzel, David Herndon and Celeste Finnerty

Citation: Cancer & Metabolism 2014 2(Suppl 1):P84

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The interaction of botanicals and AMPK signaling in the inhibition of castrate-resistant prostate cancer

Authors: Jay Whelan and Yi Zhao

Citation: Cancer & Metabolism 2014 2(Suppl 1):P85

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Phosphoinositide 3-Kinase regulates glycolysis through mobilization of Aldolase A from the actin cytoskeleton

Authors: Hai Hu, Ashish Juvekar, Costas Lyssiotis, John G Albeck, Dean R Tolan, John M Asara, Gerburg M Wulf and Lewis C Cantley

Citation: Cancer & Metabolism 2014 2(Suppl 1):P86

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Metabolic reprogramming by KSHV in cellular transformation

Authors: Ying Zhu, Suzane Ramos da Silva and Shou-Jiang Gao

Citation: Cancer & Metabolism 2014 2(Suppl 1):P88

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Preventing feedback activation of glycolytic ATP production enhances metformin cytotoxicity in breast cancer cells when oxidative phosphorylation is inhibited

Authors: Yongxian Zhuang, Daniel K Chan and W Keith Miskimins

Citation: Cancer & Metabolism 2014 2(Suppl 1):P89

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Metformin inhibits urothelial tumorigenesis in the UPII-mutant Ha-ras transgenic mouse model

Authors: Zhongbo Liu, Noriko Yokoyama, Michael Pollak and Xiaolin Zi

Citation: Cancer & Metabolism 2014 2(Suppl 1):P90

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See abstract O18

Authors:

Citation: Cancer & Metabolism 2014 2(Suppl 1):P46

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Metabolism, Diet and Disease 2014: Cancer and metabolism

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