Articles

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Metformin inhibits urothelial tumorigenesis in the UPII-mutant Ha-ras transgenic mouse model

Authors: Zhongbo Liu, Noriko Yokoyama, Michael Pollak and Xiaolin Zi

Citation: Cancer & Metabolism 2014 2(Suppl 1):P90

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Metabolic reprogramming by KSHV in cellular transformation

Authors: Ying Zhu, Suzane Ramos da Silva and Shou-Jiang Gao

Citation: Cancer & Metabolism 2014 2(Suppl 1):P88

Content type: Poster presentation

Published on: 28 May 2014

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Phosphoinositide 3-Kinase regulates glycolysis through mobilization of Aldolase A from the actin cytoskeleton

Authors: Hai Hu, Ashish Juvekar, Costas Lyssiotis, John G Albeck, Dean R Tolan, John M Asara, Gerburg M Wulf and Lewis C Cantley

Citation: Cancer & Metabolism 2014 2(Suppl 1):P86

Content type: Poster presentation

Published on: 28 May 2014

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Metformin down-regulates epithelial-mesenchymal transition (EMT) in fibroblasts from burned patients

Authors: Michael Wetzel, David Herndon and Celeste Finnerty

Citation: Cancer & Metabolism 2014 2(Suppl 1):P84

Content type: Poster presentation

Published on: 28 May 2014

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Lung tumors and non-malignant airways from patients with chronic lung inflammatory disease bear distinct genetic and epigenetic disruptions corresponding to metabolic processes involved in senescence and methylation

Authors: Emily Vucic, Kelsie Thu, Victor Martinez, Chiara Pastrello, John Yee, Igor Jurisica, Stephen Lam and Wan Lam

Citation: Cancer & Metabolism 2014 2(Suppl 1):P82

Content type: Poster presentation

Published on: 28 May 2014

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Cell proliferation and tissue remodeling are major determinants of cancer metabolism and the response to drugs targeting metabolism

Authors: Elke Markert, Philip Tedeschi, Sonia Dolphi, Kim Hirshfield, Joseph Bertino, Zoltan Oltvai and Alexei Vazquez

Citation: Cancer & Metabolism 2014 2(Suppl 1):P80

Content type: Poster presentation

Published on: 28 May 2014

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Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition

Authors: Danielle Ulanet, Abhishek Jha, Kiley Couto, Sung Choe, Amanda Wang, Hin-Koon Woo, Mya Steadman, Byron DeLaBarre, Stefan Gross, Edward Driggers, Marion Dorsch and Jonathan Hurov

Citation: Cancer & Metabolism 2014 2(Suppl 1):P78

Content type: Poster presentation

Published on: 28 May 2014

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Disruption of the endocannabinoid system is prominent in lung adenocarcinoma and associated with poor patient survival

Authors: Kelsie Thu, Roland Hubaux, Stephen Lam and Wan Lam

Citation: Cancer & Metabolism 2014 2(Suppl 1):P76

Content type: Poster presentation

Published on: 28 May 2014

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The kinase domain of PFKFB4 is required to stimulate the glucose metabolism and growth of H460 xenografts

Authors: J Clark, Y Imbert-Fernandez, J Chesney and S Telang

Citation: Cancer & Metabolism 2014 2(Suppl 1):P74

Content type: Poster presentation

Published on: 28 May 2014

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Long-term hospitalized elderly people have lowered L-carnitine and coenzyme Q₁₀ in blood than healthy elderly people

Authors: Michiyo Takahashi, Toshikazu Suzuki, Hikaru Matsumoto, Hitoshi Nukada and Naotaka Hashizume

Citation: Cancer & Metabolism 2014 2(Suppl 1):P72

Content type: Poster presentation

Published on: 28 May 2014

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Characterization of the different S6Ks isoforms interacting partners

Authors: Isadora Pavan, Flávia Ferreira, Lidia de Freitas, Mariana Tavares, Camila do Amaral and Fernando Simabuco

Citation: Cancer & Metabolism 2014 2(Suppl 1):P68

Content type: Poster presentation

Published on: 28 May 2014

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Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer

Authors: Ayesha Shajahan-Haq, Katherine Cook, Jessica Schwartz-Roberts, Ahreej Eltayeb, Diane Demas, Anni Warri, Leena Hilakivi-Clarke and Robert Clarke

Citation: Cancer & Metabolism 2014 2(Suppl 1):P66

Content type: Poster presentation

Published on: 28 May 2014

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Resveratrol differentially regulates NAMPT and SIRT1 in hepatocarcinoma cells and primary human hepatocytes

Authors: Susanne Schuster, Melanie Penke, Theresa Gorski, Anja Barnikol-Oettler, Rolf Gebhardt, Wieland Kiess and Antje Garten

Citation: Cancer & Metabolism 2014 2(Suppl 1):P65

Content type: Poster presentation

Published on: 28 May 2014

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Troglitazone suppresses tumor cell growth and glutamine metabolism through a PPAR-independent mechanism

Authors: Miriam Reynolds and Brian Clem

Citation: Cancer & Metabolism 2014 2(Suppl 1):P61

Content type: Poster presentation

Published on: 28 May 2014

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Mitochondrial complex I modulation targets metabolic plasticity in breast cancer cells

Authors: V Krishnan Ramanujan, Qijin Xu and Eva Biener-Ramanujan

Citation: Cancer & Metabolism 2014 2(Suppl 1):P59

Content type: Poster presentation

Published on: 28 May 2014

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Investigating the role of inorganic phosphate in tumor metabolism and metastasis

Authors: Cesar Perez Ramirez and Dorothea Fiedler

Citation: Cancer & Metabolism 2014 2(Suppl 1):P55

Content type: Poster presentation

Published on: 28 May 2014

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Extracellular lactate cooperates with limited glucose and glutamine to sustain breast cancer cell survival by providing ATP, NADPH, amino acids, and glutathione

Authors: Jennifer Molina, Pietro Morlacchi, Leslie Silva, Jennifer Dennison and Gordon Mills

Citation: Cancer & Metabolism 2014 2(Suppl 1):P49

Content type: Poster presentation

Published on: 28 May 2014

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Associations between diet, gut microbiota and markers of CRC risk

Authors: Tyler Culpepper, Maria Ukhanova, Xiaoyu Wang, Yijun Sun and Volker Mai

Citation: Cancer & Metabolism 2014 2(Suppl 1):P45

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Roles of endocrine FGF signaling in metabolic health and cancer

Authors: Yongde Luo, James Abbruzzese and Wallace McKeehan

Citation: Cancer & Metabolism 2014 2(Suppl 1):P43

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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LC-MS and GC-MS based metabolomics platform for cancer research

Authors: Wenyun Lu, Sisi Zhang, Xin Teng, Eugene Melamud, Mitchell A Lazar, Eileen White and Joshua D Rabinowitz

Citation: Cancer & Metabolism 2014 2(Suppl 1):P41

Content type: Poster presentation

Published on: 28 May 2014

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The biochemical mechanism of hypoxia-induced mobilization of glycogen in cultured cancer cell

Authors: Mung Kwan Long and Wong Nai Sum

Citation: Cancer & Metabolism 2014 2(Suppl 1):P37

Content type: Poster presentation

Published on: 28 May 2014

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Quantifying the demand for central carbon metabolism precursors for biosynthesis in proliferating cells

Authors: Mark Keibler, Thomas Wasylenko, Joanne Kelleher and Gregory Stephanopoulos

Citation: Cancer & Metabolism 2014 2(Suppl 1):P35

Content type: Poster presentation

Published on: 28 May 2014

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A metabolic signature of colon cancer initiating cells

Authors: Christelle Johnson, Kai-Yuan Chen, Xiaojing Liu, Pengcheng Bu, Jason Locasale and Xiling Shen

Citation: Cancer & Metabolism 2014 2(Suppl 1):P32

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Reductive carboxylation mediated oxidative stress defense supports anchorage independent cell growth

Authors: Lei Jiang, Matthew Mitsche, Ralph Deberardinis and Karine Smans

Citation: Cancer & Metabolism 2014 2(Suppl 1):P30

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Simultaneous inhibition of the estrogen receptor and 6-phosphofructo-2-kinase (PFKFB3) for the treatment of ER+ breast cancer

Authors: Yoannis Imbert-Fernandez, Sucheta Telang and Jason Chesney

Citation: Cancer & Metabolism 2014 2(Suppl 1):P29

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Mechanisms and consequences of hepatic regulation of mTORC1 by metformin

Authors: Jessica J Howell, Kristina Hellberg, Reuben J Shaw and Brendan D Manning

Citation: Cancer & Metabolism 2014 2(Suppl 1):P28

Content type: Poster presentation

Published on: 28 May 2014

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Metformin, mitochondria and cancer

Authors: Navdeep S Chandel

Citation: Cancer & Metabolism 2014 2(Suppl 1):O27

Content type: Oral presentation

Published on: 28 May 2014

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Radiation-induction of MMPs limited the NK-mediated anticancer immunity in lung cancer cells

Authors: Woong Heo, Young Shin Lee, Cheol Hun Son, Kwang Mo Yang, You Soo Park and Jae Ho Bae

Citation: Cancer & Metabolism 2014 2(Suppl 1):P26

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Biguanide therapy for diabetes and cancer & a novel methyltransferase that regulates energy expenditure and adiposity and is elevated in many cancers

Authors: Barbara B Kahn, Daniel Kraus and Qin Yang

Citation: Cancer & Metabolism 2014 2(Suppl 1):O25

Content type: Oral presentation

Published on: 28 May 2014

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Chemosensitization of leukemia cells through inhibition of NAMPT

Authors: Theresa Gorski, Stefanie Petzold-Quinque, Susanne Schuster, Melanie Penke, Sandy Richter, Wieland Kiess and Antje Garten

Citation: Cancer & Metabolism 2014 2(Suppl 1):P24

Content type: Poster presentation

Published on: 28 May 2014

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The high colon cancer risk in African Americans can be reduced by dietary modification

Authors: Stephen O’Keefe

Citation: Cancer & Metabolism 2014 2(Suppl 1):O22

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Regulation of growth and metabolism

Authors: David M Sabatini

Citation: Cancer & Metabolism 2014 2(Suppl 1):O20

Content type: Oral presentation

Published on: 28 May 2014

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Investigation of the role of Ras and other signaling kinases on the regulation of pyruvate dehydrogenase complex activity

Authors: Antonio Garcia-Trinidad, Nicky Whalley and Susan Critchlow

Citation: Cancer & Metabolism 2014 2(Suppl 1):P20

Content type: Poster presentation

Published on: 28 May 2014

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Loss of SIRT3 leads to a compensatory shift in cellular metabolism promoting cancer cell growth

Authors: Eoin McDonnell, Olga R Ilkayeva, Robert D Stevens, Michael J Muehlbauer, James R Bain, Tomas C Becker and Matthew D Hirschey

Citation: Cancer & Metabolism 2014 2(Suppl 1):O18

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Altered cancer cell metabolism and cachexia: Calculating the energetic cost of cancer

Authors: Douglas Friesen, Vickie Baracos and Jack Tuszynski

Citation: Cancer & Metabolism 2014 2(Suppl 1):P18

Content type: Poster presentation

Published on: 28 May 2014

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AMPK – roles in nutrient sensing and in cancer

Authors: D Grahame Hardie

Citation: Cancer & Metabolism 2014 2(Suppl 1):O16

Content type: Oral presentation

Published on: 28 May 2014

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Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1

Authors: Katherine Cook, Pamela Clarke, Anni Warri and Robert Clarke

Citation: Cancer & Metabolism 2014 2(Suppl 1):P16

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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The mitochondrial pyruvate carrier as a mediator of the Warburg Effect and its impact on cancer growth and metabolism

Authors: John Schell, Kristofor Olson and Jared Rutter

Citation: Cancer & Metabolism 2014 2(Suppl 1):O14

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Discovery of a PFKFB3 inhibitor for phase I trial testing that synergizes with the B-Raf inhibitor vemurafenib

Authors: Sucheta Telang, Julie O’Neal, Gilles Tapolsky, Brian Clem, Alan Kerr, Yoannis Imbert-Ferndandez and Jason Chesney

Citation: Cancer & Metabolism 2014 2(Suppl 1):P14

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Biochemical and biophysical characterization of pyruvate kinase M2 activation by L-serine

Authors: Barbara Chaneton, Finn Holding, Adam Hold, Jiska Van Der Reest, Gabriele Marciano, Marc O’Reilly and Eyal Gottlieb

Citation: Cancer & Metabolism 2014 2(Suppl 1):P12

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Antagonistic effects of MYC and hypoxia in channeling glucose and glutamine into de novo nucleotide biosynthesis

Authors: Teresa Fan, Anne Le, Zachary Stine, Ye Yang, Karen Zeller, Weiqiang Zhou, Hongkai Ji, Richard Higashi, Chi Dang and Andrew Lane

Citation: Cancer & Metabolism 2014 2(Suppl 1):O10

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Chemoprevention with the metabolism modifying drugs dichloroacetate and metformin in the Li-Fraumeni Syndrome model, Trp53^+/- mice

Authors: Anneke C Blackburn, Melissa Rooke, Yiming Li, Jane E Dahlstrom and Philip G Board

Citation: Cancer & Metabolism 2014 2(Suppl 1):P10

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Acetyl-coA synthetase 2 promotes acetate utilization and maintains cell growth under metabolic stress

Authors: Zachary Schug, Barrie Peck, Dylan Jones, Qifeng Zhang, Israt Alam, Tim Witney, Elizabeth Smethurst, Shaun Grosskurth, Adrian Harris, Susan Critchlow, Eric Aboagye, Michael Wakelam, Almut Schulze and Eyal Gottlieb

Citation: Cancer & Metabolism 2014 2(Suppl 1):O9

Content type: Oral presentation

Published on: 28 May 2014

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¹H Nuclear magnetic resonance based targeted profiling of metabolic responses induced by DNA damaging agents and PARP inhibition in MCF-7 cells

Authors: Vijesh Bhute, Daniel Beard, Stephen Kron and Sean Palecek

Citation: Cancer & Metabolism 2014 2(Suppl 1):P8

Content type: Poster presentation

Published on: 28 May 2014

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A hypothetical means of treating or preventing cancer

Authors: Steven L McKnight

Citation: Cancer & Metabolism 2014 2(Suppl 1):O7

Content type: Oral presentation

Published on: 28 May 2014

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mTORC1 stimulates nucleotide synthesis through both transcriptional and post-translational mechanisms

Authors: Issam Ben-Sahra, Stephane Ricoult, Jessica Howell, John Asara and Brendan Manning

Citation: Cancer & Metabolism 2014 2(Suppl 1):P6

Content type: Poster presentation

Published on: 28 May 2014

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Adipose tissue homeostasis is deeply disrupted by doxorubicin treatment

Authors: Helena Batatinha, Camila Souza, Edson Lima, Maria Isabel Alonso-Vale, Maysa Cruz, Roberta Da Cunha, Fabio Lira and Jose Rosa

Citation: Cancer & Metabolism 2014 2(Suppl 1):P5

Content type: Poster presentation

Published on: 28 May 2014

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Fructose-2,6-bisphosphate links glucose to survival and growth

Authors: Abdullah Yalcin, Yoannis Imbert-Fernandez, Amy Clem, Julie O’Neal, Sucheta Telang, Brian Clem and Jason Chesney

Citation: Cancer & Metabolism 2014 2(Suppl 1):O5

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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A metabolic map of hematopoietic stem cells

Authors: Michalis Agathocleous, Zeping Hu and Sean Morrison

Citation: Cancer & Metabolism 2014 2(Suppl 1):P1

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Metabolic heterogeneity in cancer

Authors: Ralph J DeBerardinis

Citation: Cancer & Metabolism 2014 2(Suppl 1):O1

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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