Articles

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Metformin inhibits urothelial tumorigenesis in the UPII-mutant Ha-ras transgenic mouse model

Authors: Zhongbo Liu, Noriko Yokoyama, Michael Pollak and Xiaolin Zi

Citation: Cancer & Metabolism 2014 2(Suppl 1):P90

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Preventing feedback activation of glycolytic ATP production enhances metformin cytotoxicity in breast cancer cells when oxidative phosphorylation is inhibited

Authors: Yongxian Zhuang, Daniel K Chan and W Keith Miskimins

Citation: Cancer & Metabolism 2014 2(Suppl 1):P89

Content type: Poster presentation

Published on: 28 May 2014

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Metabolic reprogramming by KSHV in cellular transformation

Authors: Ying Zhu, Suzane Ramos da Silva and Shou-Jiang Gao

Citation: Cancer & Metabolism 2014 2(Suppl 1):P88

Content type: Poster presentation

Published on: 28 May 2014

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Phosphoinositide 3-Kinase regulates glycolysis through mobilization of Aldolase A from the actin cytoskeleton

Authors: Hai Hu, Ashish Juvekar, Costas Lyssiotis, John G Albeck, Dean R Tolan, John M Asara, Gerburg M Wulf and Lewis C Cantley

Citation: Cancer & Metabolism 2014 2(Suppl 1):P86

Content type: Poster presentation

Published on: 28 May 2014

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Metformin down-regulates epithelial-mesenchymal transition (EMT) in fibroblasts from burned patients

Authors: Michael Wetzel, David Herndon and Celeste Finnerty

Citation: Cancer & Metabolism 2014 2(Suppl 1):P84

Content type: Poster presentation

Published on: 28 May 2014

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Lung tumors and non-malignant airways from patients with chronic lung inflammatory disease bear distinct genetic and epigenetic disruptions corresponding to metabolic processes involved in senescence and methylation

Authors: Emily Vucic, Kelsie Thu, Victor Martinez, Chiara Pastrello, John Yee, Igor Jurisica, Stephen Lam and Wan Lam

Citation: Cancer & Metabolism 2014 2(Suppl 1):P82

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Cell proliferation and tissue remodeling are major determinants of cancer metabolism and the response to drugs targeting metabolism

Authors: Elke Markert, Philip Tedeschi, Sonia Dolphi, Kim Hirshfield, Joseph Bertino, Zoltan Oltvai and Alexei Vazquez

Citation: Cancer & Metabolism 2014 2(Suppl 1):P80

Content type: Poster presentation

Published on: 28 May 2014

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Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition

Authors: Danielle Ulanet, Abhishek Jha, Kiley Couto, Sung Choe, Amanda Wang, Hin-Koon Woo, Mya Steadman, Byron DeLaBarre, Stefan Gross, Edward Driggers, Marion Dorsch and Jonathan Hurov

Citation: Cancer & Metabolism 2014 2(Suppl 1):P78

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Disruption of the endocannabinoid system is prominent in lung adenocarcinoma and associated with poor patient survival

Authors: Kelsie Thu, Roland Hubaux, Stephen Lam and Wan Lam

Citation: Cancer & Metabolism 2014 2(Suppl 1):P76

Content type: Poster presentation

Published on: 28 May 2014

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The kinase domain of PFKFB4 is required to stimulate the glucose metabolism and growth of H460 xenografts

Authors: J Clark, Y Imbert-Fernandez, J Chesney and S Telang

Citation: Cancer & Metabolism 2014 2(Suppl 1):P74

Content type: Poster presentation

Published on: 28 May 2014

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Long-term hospitalized elderly people have lowered L-carnitine and coenzyme Q₁₀ in blood than healthy elderly people

Authors: Michiyo Takahashi, Toshikazu Suzuki, Hikaru Matsumoto, Hitoshi Nukada and Naotaka Hashizume

Citation: Cancer & Metabolism 2014 2(Suppl 1):P72

Content type: Poster presentation

Published on: 28 May 2014

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Characterization of the different S6Ks isoforms interacting partners

Authors: Isadora Pavan, Flávia Ferreira, Lidia de Freitas, Mariana Tavares, Camila do Amaral and Fernando Simabuco

Citation: Cancer & Metabolism 2014 2(Suppl 1):P68

Content type: Poster presentation

Published on: 28 May 2014

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Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer

Authors: Ayesha Shajahan-Haq, Katherine Cook, Jessica Schwartz-Roberts, Ahreej Eltayeb, Diane Demas, Anni Warri, Leena Hilakivi-Clarke and Robert Clarke

Citation: Cancer & Metabolism 2014 2(Suppl 1):P66

Content type: Poster presentation

Published on: 28 May 2014

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Mitochondria, metabolism and cancer: a growing role in cancer cell differentiation and cancer cell dormancy

Authors: Roberto Scatena, Patrizia Bottoni and Bruno Giardina

Citation: Cancer & Metabolism 2014 2(Suppl 1):P64

Content type: Poster presentation

Published on: 28 May 2014

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Oncogenic signaling upstream of mTORC1 drives lipogenesis and proliferation through SREBP

Authors: Stéphane Ricoult, Jessica Yecies and Brendan Manning

Citation: Cancer & Metabolism 2014 2(Suppl 1):P62

Content type: Poster presentation

Published on: 28 May 2014

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Pyruvate dehydrogenase activity is required for optimal growth under lipid deficient conditions

Authors: Kartik Rajagopalan and Ralph DeBerardinis

Citation: Cancer & Metabolism 2014 2(Suppl 1):P58

Content type: Poster presentation

Published on: 28 May 2014

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Metabolic mechanisms regulating distinct steps of the melanoma metastatic cascade

Authors: Elena Piskounova, Michalis Agathocleous, Zeping Hu and Sean Morrison

Citation: Cancer & Metabolism 2014 2(Suppl 1):P56

Content type: Poster presentation

Published on: 28 May 2014

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Comprehensive quantitation of metabolite concentrations, gross reaction fluxes, and reaction free energies across cells from four organisms

Authors: Junyoung Park, Sara Rubin, Yi-Fan Xu, Daniel Amador-Noguez, Jing Fan and Joshua Rabinowitz

Citation: Cancer & Metabolism 2014 2(Suppl 1):P54

Content type: Poster presentation

Published on: 28 May 2014

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Extracellular lactate cooperates with limited glucose and glutamine to sustain breast cancer cell survival by providing ATP, NADPH, amino acids, and glutathione

Authors: Jennifer Molina, Pietro Morlacchi, Leslie Silva, Jennifer Dennison and Gordon Mills

Citation: Cancer & Metabolism 2014 2(Suppl 1):P49

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Associations between diet, gut microbiota and markers of CRC risk

Authors: Tyler Culpepper, Maria Ukhanova, Xiaoyu Wang, Yijun Sun and Volker Mai

Citation: Cancer & Metabolism 2014 2(Suppl 1):P45

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Roles of endocrine FGF signaling in metabolic health and cancer

Authors: Yongde Luo, James Abbruzzese and Wallace McKeehan

Citation: Cancer & Metabolism 2014 2(Suppl 1):P43

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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LC-MS and GC-MS based metabolomics platform for cancer research

Authors: Wenyun Lu, Sisi Zhang, Xin Teng, Eugene Melamud, Mitchell A Lazar, Eileen White and Joshua D Rabinowitz

Citation: Cancer & Metabolism 2014 2(Suppl 1):P41

Content type: Poster presentation

Published on: 28 May 2014

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The biochemical mechanism of hypoxia-induced mobilization of glycogen in cultured cancer cell

Authors: Mung Kwan Long and Wong Nai Sum

Citation: Cancer & Metabolism 2014 2(Suppl 1):P37

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Quantifying the demand for central carbon metabolism precursors for biosynthesis in proliferating cells

Authors: Mark Keibler, Thomas Wasylenko, Joanne Kelleher and Gregory Stephanopoulos

Citation: Cancer & Metabolism 2014 2(Suppl 1):P35

Content type: Poster presentation

Published on: 28 May 2014

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CRTC1 transcriptional coactivator is required for hepatitis B virus gene expression and replication

Authors: Hei-Man Vincent Tang, Wei-Wei Gao, Chi-Ping Chan, Kin-Hang Kok and Dong-Yan Jin

Citation: Cancer & Metabolism 2014 2(Suppl 1):P31

Content type: Poster presentation

Published on: 28 May 2014

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Simultaneous inhibition of the estrogen receptor and 6-phosphofructo-2-kinase (PFKFB3) for the treatment of ER+ breast cancer

Authors: Yoannis Imbert-Fernandez, Sucheta Telang and Jason Chesney

Citation: Cancer & Metabolism 2014 2(Suppl 1):P29

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Metformin, mitochondria and cancer

Authors: Navdeep S Chandel

Citation: Cancer & Metabolism 2014 2(Suppl 1):O27

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Inhibition of glutamine uptake regulates mTORC1, glutamine metabolism and cell growth in prostate cancer

Authors: Qian Wang, Rae-Anne Hardie, Seher Balaban, Mark Schreuder, Andrew Hoy, Michelle van Geldermalsen, Ladan Fazli, Rajini Nagarajah, Charles Bailey, John Rasko and Jeff Holst

Citation: Cancer & Metabolism 2014 2(Suppl 1):P27

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Biguanide therapy for diabetes and cancer & a novel methyltransferase that regulates energy expenditure and adiposity and is elevated in many cancers

Authors: Barbara B Kahn, Daniel Kraus and Qin Yang

Citation: Cancer & Metabolism 2014 2(Suppl 1):O25

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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AMPK regulated metabolic programing: oncogenic or growth suppressive? Evolving lessons from genetic and pharmacologic studies

Authors: Xiaona Liu, Rishi Raj Chhipa, Lionel ML Chow, Matthew Wortman, Christopher McPherson, Ady Kendler and Biplab Dasgupta

Citation: Cancer & Metabolism 2014 2(Suppl 1):O23

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Metformin suppresses pediatric acute myeloid leukemia cell viability and clonogenicity

Authors: Anilkumar Gopalakrishnapillai, E Anders Kolb and Sonali Barwe

Citation: Cancer & Metabolism 2014 2(Suppl 1):P23

Content type: Poster presentation

Published on: 28 May 2014

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Extracts from medicinal plants inhibit cancer cell proliferation, induce apoptosis in ovary, lung and neuronal cancer cell lines

Authors: Wafa Ghali, David Vaudry, Thierry Jouenne and Mohamed Nejib Marzouki

Citation: Cancer & Metabolism 2014 2(Suppl 1):P21

Content type: Poster presentation

Published on: 28 May 2014

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A Drosophila model linking diet-induced metabolic disease and cancer

Authors: Susumu Hirabayashi, Thomas Baranski and Ross Cagan

Citation: Cancer & Metabolism 2014 2(Suppl 1):O19

Content type: Oral presentation

Published on: 28 May 2014

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Effects of the ghrelin receptor agonist anamorelin on lean body mass in cancer patients with cachexia; results from a Phase II randomized, double blind, multicenter study

Authors: Jose M Garcia, Ying Yan, Elizabeth Manning-Duus and John Friend

Citation: Cancer & Metabolism 2014 2(Suppl 1):P19

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Regulation of metabolism by a neuroendocrine FGF signaling pathway

Authors: David J Mangelsdorf and Steven A Kliewer

Citation: Cancer & Metabolism 2014 2(Suppl 1):O17

Content type: Oral presentation

Published on: 28 May 2014

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Inhibiting glucose-regulated protein 78 modulates lipid metabolism through controlling stearoyl-CoA desaturase 1

Authors: Katherine Cook, Pamela Clarke, Anni Warri and Robert Clarke

Citation: Cancer & Metabolism 2014 2(Suppl 1):P16

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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The in vivo function of TIGAR, a p53 target gene that regulates glucose metabolism

Authors: Eric Cheung, Pearl Lee, Celia Berkers, Karen Blyth, Owen Sansom and Karen Vousden

Citation: Cancer & Metabolism 2014 2(Suppl 1):P15

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Discovery of a PFKFB3 inhibitor for phase I trial testing that synergizes with the B-Raf inhibitor vemurafenib

Authors: Sucheta Telang, Julie O’Neal, Gilles Tapolsky, Brian Clem, Alan Kerr, Yoannis Imbert-Ferndandez and Jason Chesney

Citation: Cancer & Metabolism 2014 2(Suppl 1):P14

Content type: Poster presentation

Published on: 28 May 2014

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Biochemical and biophysical characterization of pyruvate kinase M2 activation by L-serine

Authors: Barbara Chaneton, Finn Holding, Adam Hold, Jiska Van Der Reest, Gabriele Marciano, Marc O’Reilly and Eyal Gottlieb

Citation: Cancer & Metabolism 2014 2(Suppl 1):P12

Content type: Poster presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Role of autophagy in K-RAS- and B-RAF-driven lung cancers

Authors: Eileen White

Citation: Cancer & Metabolism 2014 2(Suppl 1):O11

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Antagonistic effects of MYC and hypoxia in channeling glucose and glutamine into de novo nucleotide biosynthesis

Authors: Teresa Fan, Anne Le, Zachary Stine, Ye Yang, Karen Zeller, Weiqiang Zhou, Hongkai Ji, Richard Higashi, Chi Dang and Andrew Lane

Citation: Cancer & Metabolism 2014 2(Suppl 1):O10

Content type: Oral presentation

Published on: 28 May 2014

This article is part of a Supplement: Volume 2 Supplement 1
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Chemoprevention with the metabolism modifying drugs dichloroacetate and metformin in the Li-Fraumeni Syndrome model, Trp53^+/- mice

Authors: Anneke C Blackburn, Melissa Rooke, Yiming Li, Jane E Dahlstrom and Philip G Board

Citation: Cancer & Metabolism 2014 2(Suppl 1):P10

Content type: Poster presentation

Published on: 28 May 2014

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¹H Nuclear magnetic resonance based targeted profiling of metabolic responses induced by DNA damaging agents and PARP inhibition in MCF-7 cells

Authors: Vijesh Bhute, Daniel Beard, Stephen Kron and Sean Palecek

Citation: Cancer & Metabolism 2014 2(Suppl 1):P8

Content type: Poster presentation

Published on: 28 May 2014

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Oncogenic switching of hypoxia signalling pathways

Authors: Peter J Ratcliffe

Citation: Cancer & Metabolism 2014 2(Suppl 1):O8

Content type: Oral presentation

Published on: 28 May 2014

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mTORC1 stimulates nucleotide synthesis through both transcriptional and post-translational mechanisms

Authors: Issam Ben-Sahra, Stephane Ricoult, Jessica Howell, John Asara and Brendan Manning

Citation: Cancer & Metabolism 2014 2(Suppl 1):P6

Content type: Poster presentation

Published on: 28 May 2014

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Nutrition and metabolic factors in cancer causation and prevention

Authors: Elio Riboli

Citation: Cancer & Metabolism 2014 2(Suppl 1):O6

Content type: Oral presentation

Published on: 28 May 2014

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Dual mode of action of metformin on mitochondrial metabolism

Authors: Sylvia Andrzejewski, Simon-Pierre Gravel, Julie St-Pierre and Michael N Pollak

Citation: Cancer & Metabolism 2014 2(Suppl 1):P4

Content type: Poster presentation

Published on: 28 May 2014

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Metabolic analysis of the loss of Rb1 in vivo

Authors: Brandon N Nicolay, Paul S Danielian, Wilhelm Haas, Gregory Stephanopoulos, Jacqueline A Lees and Nicholas J Dyson

Citation: Cancer & Metabolism 2014 2(Suppl 1):O4

Content type: Oral presentation

Published on: 28 May 2014

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Doxorubicin leads to impaired insulin signaling in skeletal muscle

Authors: Edson Alves de Lima Junior, Camila Oliveira de Souza, Alexandre Abílio de Souza Teixeira, Helena Angélica Batatinha, Fábio de Santos Lira and José César Rosa Neto

Citation: Cancer & Metabolism 2014 2(Suppl 1):P2

Content type: Poster presentation

Published on: 28 May 2014

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Metabolic heterogeneity in cancer

Authors: Ralph J DeBerardinis

Citation: Cancer & Metabolism 2014 2(Suppl 1):O1

Content type: Oral presentation

Published on: 28 May 2014

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