Table 2 Fructose effects in various types of cancer cells
From: Fructose contributes to the Warburg effect for cancer growth
Types | Fructose effects | Material | Ref. |
|---|---|---|---|
Pancreatic cancer | Activation of non-oxidative PPP Transketolase activation Nucleic acid production | Cultured cell line (CaPan-I, CaPan II, HPAF2, Aspc1, Panc-1, MiaPaCa-2) | [64] |
Lung cancer | Fatty acid synthesis ATP production | Human bronchial epithelial cell (BEAS-2B); NSCLC cells (PC-9, H1299, A549, HCC-827, H1975) | [60] |
Breast cancer | Adhesion to endothelium Tumor growth Metastasis 12 LOX signals | Cultured cell (MDA-MB-468 cell, MCF-7 cell) Mice (FVB/N-Tg(MMTVneu)202Mul/J) | |
Intestinal cancer | Fructokinase Lactate production | Mice | [67] |