Cancer & Metabolism volume 2, Article number: 127 (2014)
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Anne Brunet (Stanford University) discussed the metabolic regulation of aging using the C. elegans model. She focused on histone methylation as deficiencies in trimethylation of histone 3 at lysine 4 (H3K4me3) were found to increase lifespan. Regulation of H3K27me3 was also involved in lifespan determination. Brunet further discussed the importance of fat metabolism, in particular the different type of fatty acids, in H3K4me3-deficient worms and how this relates to longevity.
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Kamphorst JJ, Murphy DJ: The 2014 Beatson International Cancer Conference: Powering the Cancer Machine. Cancer and Metabolism. 2014, 2: 25-10.1186/2049-3002-2-25.
The online version of the original article can be found at 10.1186/2049-3002-2-25
Kamphorst, J.J., Murphy, D.J. Erratum to: The 2014 Beatson international cancer conference: powering the cancer machine. Cancer Metab 2, 127 (2014). https://doi.org/10.1186/s40170-014-0127-8