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Table 1 Baseline clinical and biochemical characteristics of subjects

From: Metabolic changes preceding bladder cancer occurrence among Korean men: a nested case-control study from the KCPS-II cohort

 

Set 1

Set 2

 

Total (n = 70)

pa

Total (n=62)

pa

pb

Control (n = 35)

Bladder cancer occurrence (n = 35)

Control (n = 31)

Bladder cancer occurrence (n = 31)

Age (year)

52.02 ± 1.10

54.51 ± 1.24

0.139

50.14 ± 1.78

50.26 ± 1.76

0.910†

 

Current smoker n, (%)

13 (37.1)

13 (37.1)

0.737

14 (45.2)

19 (61.3)

0.112

 

Body mass index (kg/m2)

25.19 ± 0.34

24.88 ± 0.44

0.666

23.32 ± 0.47

24.73 ± 0.48

0.043

 

Waist circumference (cm)

87.73 ± 1.09

87.50 ± 1.23

0.919

83.48 ± 1.23

86.76 ± 1.09

0.045

0.476

Systolic blood pressure (mmHg)

125.40 ± 2.72

122.92 ± 2.68

0.507

123.71 ± 2.38

121.10 ± 2.56

0.528†

0.606

Diastolic blood pressure (mmHg)

81.69 ± 1.99

76.23 ± 1.76

0.041∮

77.89 ± 1.39

75.72 ± 1.46

0.302†

0.370

Glucose (mg/dL)

96.09 ± 2.44

98.17 ± 2.81

0.368†

96.82 ± 5.04

96.49 ± 5.59

0.578†

0.760

White blood cell (103/μL)

6.03 ± 0.23

6.35 ± 0.24

0.251†

5.99 ± 0.27

6.52 ± 0.28

0.140∮

0.072

Albumin (g/dL)

4.64 ± 0.05

4.64 ± 0.04

0.920

4.45 ± 0.05

4.42 ± 0.04

0.704

0.467

Total cholesterol (mg/dL)

191.22 ± 6.38

195.61 ± 5.83

0.613

188.57 ± 6.62

201.73 ± 6.34

0.157

0.199

Triglyceride (mg/dL)

166.58 ± 15.33

148.42 ± 11.92

0.328∮

164.03 ± 16.87

170.30 ± 15.55

0.654∮

0.925

HDL cholesterol (mg/dL)

48.32 ± 1.86

48.01 ± 1.37

0.943∮

47.41 ± 1.26

47.67 ± 1.11

0.927†

0.508

LDL cholesterol (mg/dL)

114.50 ± 5.95

118.17 ± 5.33

0.639

112.82 ± 6.07

123.74 ± 6.37

0.216

0.260

AST (IU/L)

29.88 ± 3.94

24.31 ± 1.56

0.213†

33.28 ± 5.65

32.73 ± 6.98

0.921†

0.787

ALT (IU/L)

38.31 ± 9.52

28.30 ± 2.91

0.732†

34.02 ± 4.44

33.50 ± 4.09

0.693†

0.714

GGT (IU/L)

70.44 ± 16.93

44.82 ± 5.00

0.317†

86.03 ± 22.03

60.59 ± 8.52

0.632†

0.427

Bilirubin (mg/dL)

0.91 ± 0.07

0.95 ± 0.07

0.645∮

0.97 ± 0.08

0.88 ± 0.04

0.508†

0.636

Uric acid (mg/dL)

5.99 ± 0.27

6.10 ± 0.20

0.737

5.88 ± 0.23

6.00 ± 0.23

0.706

0.621

Blood urea nitrogen (mg/dL)

16.24 ± 1.77

14.87 ± 0.77

0.935†

15.18 ± 0.67

15.12 ± 0.66

0.949†

0.697

Creatinine (mg/dL)

1.25 ± 0.20

1.04 ± 0.03

0.999†

1.14 ± 0.03

1.08 ± 0.03

0.999†

0.079

  1. Mean ± standard error (SE). Comparisons between the two groups (control vs. bladder cancer occurrence). Continuous variables were tested by an independent t-test, and variables marked with ∮ were tested by logarithmic transformation. Continuous variables with a nonnormal distribution even after logarithmic transformation were tested by a Mann-Whitney U-test, and pa-values are marked with †. Pb-values are BMI-adjusted pa-values. Smoking status was tested by a chi-squared test. AST aspartate aminotransferase, ALT alanine aminotransferase, GGT γ-glutamyltransferase, HDL high-density lipoprotein, LDL low-density lipoprotein
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Cancer & Metabolism

ISSN: 2049-3002