Cases (n = 902) | Controls (n = 902) | p-value | |
---|---|---|---|
Age at baseline | 56.2 (7.4) | 56.2 (7.4) | 0.826 |
Age at diagnosis | 66.5 (9.1) | - | - |
Sex | 1.000 | ||
Men | 462 (51.2%) | 462 (51.2%) | |
Women | 440 (48.8%) | 440 (48.8%) | |
BMI (kg/m2)a | 26.7 (4.0) | 26.3 (4.0) | 0.015 |
Cohort | 1.000 | ||
VIP | 820 (91%) | 820 (91%) | |
MONICA | 82 (9%) | 82 (9%) | |
Freeze and thaw cyclesb | < 0.001 | ||
0 | 755 (84%) | 752 (83%) | |
1 | 79 (9%) | 109 (12%) | |
2 | 44 (5%) | 40 (4%) | |
3 | 24 (3%) | 1 (0%) | |
Fasting status | 1.000 | ||
0–4 h | 27 (3%) | 27 (3%) | |
4–8 h | 125 (14%) | 125 (14%) | |
> 8 h | 750 (83%) | 750 (83%) | |
Storage time (years) | 20.9 (5.7) | 20.9 (5.7) | 0.976 |
Smoking status | 0.221 | ||
Nonsmoker | 364 (41%) | 400 (45%) | |
Former smoker | 335 (38%) | 307 (35%) | |
Current smoker | 187 (21%) | 173 (20%) | |
Missing | 16 | 22 | |
Education | 0.359 | ||
Elementary school | 348 (39%) | 369 (42%) | |
Secondary school | 397 (45%) | 362 (41%) | |
Postsecondary school | 141 (16%) | 157 (18%) | |
Missing | 16 | 14 | |
Diabetes | 0.069 | ||
Yes | 34 (4%) | 20 (2%) | |
No | 863 (96%) | 872 (98%) | |
Missing | 5 | 10 | |
Recreational physical activity | 0.432 | ||
Never | 373 (49%) | 337 (44%) | |
Now and then | 201 (26%) | 212 (28%) | |
1–2 times/week | 98 (14%) | 103 (14%) | |
2–3 times/week | 61 (8%) | 76 (10%) | |
> 3 times/week | 36 (5%) | 30 (4%) | |
Missing | 133 | 144 | |
Alcohol intake (g/day)c | 4.1 (5.0) | 3.8 (4.7) | 0.624 |
Tumor location | - | ||
Proximal colon | 286 (32%) | - | |
Distal colon | 266 (30%) | - | |
Rectum | 342 (38%) | - | |
Missing | 8 | - | |
Stage | - | ||
Stages I–II | 426 (51%) | - | |
Stages III–IV | 417 (49%) | - | |
Missing | 59 | - | |
BRAFd | - | ||
Mutation | 140 (20%) | - | |
Wild type | 565 (80%) | - | |
Missing | 197 | - | |
KRASd | - | ||
Mutation | 154 23%) | - | |
Wild type | 504 (77%) | - | |
Missing | 244 | - | |
KRAS/BRAFd | - | ||
BRAF | 140 (22%) | - | |
KRAS | 154 (24%) | - | |
Both wild type | 354 (55%) | - | |
Missing | 254 | - | |
MSI status | - | ||
MSS | 568 (87%) | - | |
MSI | 87 (13%) | - | |
Missing | 247 | - |