Fig. 2

The relationship between patient characteristics and recurrence rates in breast cancer patients with healthy weight vs obesity defined by BMI. Forest plot shows adjusted HR (95% CI) of breast cancer recurrence for patients with obesity (BMI ≥ 30.0) compared with patients with healthy weight (BMI 18.5–24.9), according to stratified patient characteristics. *BCR = breast cancer recurrence. **The stratified analyses were adjusted for the following co-variables excluding the stratified variable of interest: age, histological grade, tumor size, nodal status, estrogen-receptor status, surgery, planned adjuvant radio-, chemo-, and endocrine therapy. ***The relative excess risk due to interaction with 95% CI for socioeconomic position was 0.94 (0.11–1.76) indicating a super-additive interaction effect, suggesting that the response to multimodal exposure are greater than the sum of the independent responses to low socioeconomic position or obesity alone