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Table 1 Associations of PDK1 and PDK2 expression with clinical features of HNC patients

From: PDK1- and PDK2-mediated metabolic reprogramming contributes to the TGFβ1-promoted stem-like properties in head and neck cancer

 

No. of HNC

PDK1a

PDK2b

Low

High

P

Low

High

P

Sex

 F

14

11

3

0.887

7

7

0.266

 M

56

43

13

19

37

Stage

 I

11

9

2

0.688

7

4

0.048*

 II+III+IV

59

45

14

19

40

Age (years)

       

 <55

37

28

9

0.757

19

18

0.009*

55

33

26

7

7

26

T

 T1+T2

37

29

8

0.794

15

22

0.533

 T3+T4

33

25

8

11

22

N

 N0

51

40

11

0.674

19

32

0.975

 N1+N2

19

14

5

7

12

M

 M0

67

51

16

0.430

24

43

0.681

 M1

2

2

0

1

1

Grade

 1

23

15

8

0.298

6

17

0.579

 2

25

21

4

10

15

 3

10

8

2

3

7

Location

 Larynx

37

31

6

0.046*

12

25

0.319

 Oral cavity

20

12

8

4

16

  1. aLow score = 1~2. High score= 3~5
  2. bLow score = 1~3. High score= 4~6
  3. *P<0.05