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Fig. 1 | Cancer & Metabolism

Fig. 1

From: Tadalafil increases the antitumor activity of 5-FU through inhibiting PRMT5-mediated glycolysis and cell proliferation in colorectal cancer

Fig. 1

PRMT5 was highly expressed in colorectal cancer and indicated a poor prognosis. A and B Expression of PRMT5 in CRC patients from GSE8671 (A) and GSE32323 (B). C Typical images of PRMT5 expression in CRC patients. D The expression levels of PRMT5 were scored semiquantitatively based on staining intensity and distribution in 103 paired CRC tissues positioned in a tissue microarray. Scale bar (red line) = 100 μm. E Survival analysis of PRMT5 in TCGA database (left, colon and rectum adenocarcinoma; right, rectum adenocarcinoma only). ***P < 0.001

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Cancer & Metabolism

ISSN: 2049-3002