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Fig. 7 | Cancer & Metabolism

Fig. 7

From: Blocking lncRNA-SNHG16 sensitizes gastric cancer cells to 5-Fu through targeting the miR-506-3p-PTBP1-mediated glucose metabolism

Fig. 7

PTBP1 promotes glycolysis of GC cells. a ECAR, b glucose uptake, and c mRNA expressions of glycolysis key enzymes from AGS cells without or with PTBP1 silencing. d, e Effects of PTBP1 knocking down by shRNA in GC cells. f Heatmap from transcriptome sequencing analysis shows differentially expressed mRNAs in AGS parental and 5-Fu-resistant cells. Red: upregulation; Green: downregulation of gene expressions. g The top representatively upregulated and downregulated GO enrichment biological processes by shPTBP1. Data were presented as mean±S.D. *p<0.05; **p<0.01

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Cancer & Metabolism

ISSN: 2049-3002