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Table 1 Demographic characteristics of training cohort participants

From: Integrative analysis of plasma metabolomics and proteomics reveals the metabolic landscape of breast cancer

Parameters

Healthy controls

Benign patients

BC patients

P value

Number of samples

20

30

75

 

Age (years, mean ± SD)

44.68 ± 13.20

43.60 ± 11.93

52.03 ± 10.62

0.001

Gender (female)

20

30

75

-

BMI (mean±SD, kg/m2)

22.47 ± 2.81

22.49 ± 2.29

23.02 ± 3.28

0.634

Tumor molecular type

NA

NA

 

-

 Luminal A

  

19 (25.3%)

 

 Luminal B

  

34 (45.3%)

 

 HER-2+

  

14 (18.7%)

 

 Basal-like

  

8 (10.7%)

 

Menopause

   

0.435

 Post-menopausal women

7 (35%)

8 (26.7%)

30 (40%)

 

 Pre-menopausal women

13 (65%)

22 (73.3%)

45 (60%)

 

Tumor stage

NA

NA

 

-

 I

  

31 (41.33%)

 

 II

  

33 (44%)

 

 III

  

11 (14.67%)

 
  1. Continuous variables (age and BMI) were tested with one-way ANOVA analysis. Dichotomous data (menopause) was tested with chi-square test, assigned “post-menopausal women” = 1 and “pre-menopausal women” = 2. “P < 0.05” was considered as a statistical significance
  2. Abbreviations: BC breast cancer, BMI body mass index, NA not applicable