Integration of global metabolomics and lipidomics approaches reveals the molecular mechanisms and the potential biomarkers for postoperative recurrence in early-stage cholangiocarcinoma

Table 2 Pathway analysis of differential metabolites from lipidomics

Pathways	Hits	Raw p	Holm adjust	FDR	Impact
Glycerophospholipid metabolism	2	0.0009	0.005	0.003	0.199
Glycerolipid metabolism	1	0.0301	0.030	0.030	0.014
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1	0.0008	0.005	0.003	0.004
Arachidonic acid metabolism	1	0.0060	0.024	0.007	0
Linoleic acid metabolism	1	0.0060	0.024	0.007	0
Alpha-Linolenic acid metabolism	1	0.0060	0.024	0.007	0

Hits matched metabolites in pathway, Raw p original p value calculated from enrichment analysis, Holm adjust adjust p value from Bonferroni method, FDR false discovery rate, Impact pathway impact calculated from topology analysis

ISSN: 2049-3002