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Table 3 Enrichment for CRC bacteria in different basal environments and model subsets

From: Metabolic models predict bacterial passengers in colorectal cancer

Basal environment Model subset Score Max W CRC enrich.
p value
(null 1)
CRC enrich.
p value
(null 2)
Mann-Whitney
U statistic
Mann-Whitney
p value
Adj. p value#
MAMBO All MI 0.2813 1.00E−04 1.00E−04 109720.5 1.79E−08 6.90E−08
  SGA 0.2620 1.00E−04 1.00E−04 103113 2.20E−05 4.57E−05
  MR 0.3255 1.00E−04 1.00E−04 107855.5 1.14E−07 3.85E−07
Gut MI 0.3995 1.00E−04 1.00E−04 10156 2.09E−05 4.57E−05
  SGA 0.3330 1.00E−04 1.00E−04 8694 1.98E−02 2.97E−02
  MR 0.4258 2.00E−04 1.00E−04 9491 5.28E−04 1.02E−03
AGORA MI 0.4302 1.00E−04 1.00E−04 43996 1.53E−15 1.38E−14
  SGA 0.3446 1.00E−04 1.00E−04 38949 1.61E−07 4.83E−07
  MR 0.4423 1.00E−04 1.00E−04 42642 2.51E−13 1.69E−12
Western diet All MI 0.3193 1.00E−04 1.00E−04 113411.5 1.44E−10 6.48E−10
SGA 0.1035 9.16E−02 9.74E−02 86876.5 2.73E−01 2.73E−01
MR 0.1327 2.17E−02 1.94E−02 91885 3.82E−02 5.16E−02
Gut MI 0.4713 1.00E−04 1.00E−04 10493 2.57E−06 6.31E−06
SGA 0.2607 1.36E−02 1.59E−02 8417.5 4.27E−02 5.49E−02
MR 0.3544 5.00E−04 3.00E−04 9265.5 9.35E−04 1.68E−03
AGORA MI 0.4231 1.00E−04 1.00E−04 44395.5 2.82E−16 3.81E−15
SGA 0.1744 8.80E−03 8.70E−03 31390.5 1.16E−01 1.36E−01
MR 0.2412 1.00E−04 1.00E−04 34690.5 1.01E−03 1.70E−03
High-fiber diet All MI 0.3179 1.00E−04 1.00E−04 113424 1.41E−10 6.48E−10
SGA 0.1117 6.62E−02 6.56E−02 86914 2.66E−01 2.73E−01
MR 0.1274 5.90E−02 2.91E−02 91129 4.77E−02 5.85E−02
Gut MI 0.4713 1.00E−04 1.00E−04 10495 2.53E−06 6.31E−06
SGA 0.2273 3.93E−02 3.78E−02 7782 1.98E−01 2.14E−01
MR 0.2831 7.70E−03 7.10E−03 8384 3.10E−02 4.41E−02
AGORA MI 0.4197 1.00E−04 1.00E−04 44399.5 2.77E−16 3.81E−15
SGA 0.1641 1.69E−02 1.71E−02 30795 1.88E−01 2.12E−01
MR 0.2102 1.50E−03 1.90E−03 33887.5 3.59E−03 5.70E−03
  1. #adjusted p values <0.05 were considered significant