Fig. 8

HK2 is not required for normal hematpoiesis. Mice with HK2-deficient bone marrow were generated (Hk2^Fl/Fl;Vav1-iCre⁺, referred to as BM-Hk2^−/−) a Western blot for protein expression of HK2 and β-actin in bone marrow. Representative of four independent experiments b Peripheral blood counts of indicated hematopoietic lineages in adult WT and Hk2^Fl/Fl; Vav1-iCre⁺ mice. n = 8 WT, 6 Hk2^Fl/Fl; Vav1-iCre⁺ mice. In all panels, biological replicates shown, at least two independent experiments performed, error bars represent mean ± SEM, unpaired t test, *p < 0.05; **p < 0.01. NS = not significant