Fig. 3

PKM2 loss delays KP soft tissue sarcoma initiation. KP M2^+/+ or KP M2^fl/fl mice were injected intramuscularly with Ad5-CMV-Cre (a) and the onset of palpable sarcomas was monitored, p value by log-rank test is 0.003 (b). The percentage of total mice (n) with sarcomas by 62 days (gray box) is indicated. c Time for palpable tumor formation, p value using unpaired t test is 0.04