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Fig. 2 | Cancer & Metabolism

Fig. 2

From: Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma

Fig. 2

A high PKM2/PKM1 expression ratio predicts poor prognosis. a Kaplan–Meier 5-year survival analysis comparing patients in the top quintile of PKM2/PKM1 expression ratio (n = 51; red) and those in the bottom quintile (n = 51; blue). Log-rank test p value is shown. b Results of univariate and multivariable Cox proportional hazards model on overall survival in the TCGA sarcoma cohort (all patients). Increasing PKM2/PKM1 expression ratio shows a significant association with poor survival after controlling for other characteristics

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Cancer & Metabolism

ISSN: 2049-3002