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Fig. 6 | Cancer & Metabolism

Fig. 6

From: Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner

Fig. 6

PC and PE synthesis is downregulated in orthotopic IDHmut glioma xenografts. a Representative axial T2-weighted MR images of U87IDHwt and U87IDHmut orthotopic tumor-bearing mice. Tumor regions have been manually contoured in white. PC (b), PE (c), CKα expression (d), CK activity (e), EK activity (f), and HIF-1α (g) in U87IDHwt and U87IDHmut tumor xenografts

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Cancer & Metabolism

ISSN: 2049-3002