Fig. 6
From: The role of HIF-1 in oncostatin M-dependent metabolic reprogramming of hepatic cells
Effect of OSM treatment on central carbon metabolism of HepG2 and JHH-4. a Relative carbon contribution to citrate. b PDC activity determined by the ratio of M2 isotopologues of citrate to M3 isotopologues of lactate, from [13C6]glucose. c Reductive glutamine contribution to citrate, determined by the ratio of M5 isotopologues of citrate to M5 isotopologues of glutamate, from [13C5]glutamine. All error bars indicate the standard deviation. All error bars are calculated from at least two independent replicates (n>=2). Metabolites were extracted after 36 h of indicated treatment