Fig. 3
From: Metabolic plasticity maintains proliferation in pyruvate dehydrogenase deficient cells
PDH suppression increases dependence on extracellular lipids for growth. a Uptake of BODIPY-labeled fatty acids imaged by fluorescence microscopy after 24 h of culture. b Quantification of BODIPY fluorescence intensity. c Doubling time calculated from 12-day cultures under normal (left) and delipidated (right) conditions. d Cell count after 4 days of culture in delipidated serum, with or without a 50 μM each of palmitate and oleate. Data are the average and SD of biological triplicates. *P < 0.05; **P < 0.005. Abbreviations: FFAs, free fatty acids