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Figure 1 | Cancer & Metabolism

Figure 1

From: TIGAR, TIGAR, burning bright

Figure 1

TIGAR functions as a fructose-2,6-bisphosphatase. Schematic of glycolysis, the pentose phosphate pathway (PPP) and the hexosamine pathway. TIGAR is predicted to promote both the PPP and hexosamine pathways by lowering the levels of fructose-2,6-bisphosphate and redirecting glycolytic intermediates.

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Cancer & Metabolism

ISSN: 2049-3002