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Fig. 4 | Cancer & Metabolism

Fig. 4

From: Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cells

Fig. 4

Serine efflux (J22) for cells metabolizing [1,2-13C] glucose. Serine (M-M3) was quantified by TQ-MS as detailed in the “Methods”. The efflux rate was calculated as the sum of all serine isotopologues in the ECF divided by 60-min incubation (averaged from two incubation periods). Data are mean ± SEM of six experiments for each cell line. Significant differences were assessed by one-way ANOVA with Tukey’s post hoc test. Bars sharing common letters are not significantly different

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