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Fig. 11 | Cancer & Metabolism

Fig. 11

From: Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cells

Fig. 11

Bi-plot of Loadings and Scores from principal component analysis of Tables 5 and 6 data. To simplify the plot, dependent flux Loadings were consolidated. Abbreviations: Gly: glycolysis (average of J2a, J2b, J2c, J4); Gln cons: glutamine consumers (average of J10a, J10b); Mito ox: mitochondrial oxidation (J5, J6a, J11a, J12f, J14, J16, JRR); OxPPP: oxidative PPP (J1); fNonPPP: forward non-oxidative PPP consuming R5P (J3f); rNonPPP: reverse non-oxidative PPP producing R5P (J3r); FA syn: fatty acid synthesis (average of J12r, J13); Ser syn: serine synthesis (J19); GSH syn: glutathione synthesis (J18); NT syn: nucleotide synthesis (J9, J21); and ME: malic enzyme (J7)

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Cancer & Metabolism

ISSN: 2049-3002