Fig. 10From: Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cellsBi-plot of Loadings and Scores from principal component analysis of Table 4 data. Flux ratios R8–R11 (see Table 4) were determined by Model 3 to simulate 13C lactate labeling from [5-13C] glutamine. The Scores from all experiments clustered into distinct groups by cell line. The arrows reflect the Loadings and show the correlations among the variables R8–R11 and respiration rate (RR) used to simulate 13C lactate labelingBack to article page