Table 2 Significantly affected pathways by HDMTX treatment
Pathways | P | −Log(p) | FDR | Impact |
|---|---|---|---|---|
Pyrimidine metabolism | 0.0087 | 2.0600 | 0.65 | 0.09 |
Phenylalanine, tyrosine, and tryptophan biosynthesis | 0.0154 | 1.8100 | 0.65 | 0.50 |
Phenylalanine metabolism | 0.0382 | 1.4200 | 1.00 | 0.36 |
Arginine biosynthesis | 0.0531 | 1.2800 | 1.00 | 0.23 |
Pantothenate and CoA biosynthesis | 0.0714 | 1.1500 | 1.00 | 0.00 |
Beta-alanine metabolism | 0.0787 | 1.1000 | 1.00 | 0.00 |
Fatty acid degradation | 0.1420 | 0.8480 | 1.00 | 0.00 |
Aminoacyl-tRNA biosynthesis | 0.1720 | 0.7640 | 1.00 | 0.00 |