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Fig. 6 | Cancer & Metabolism

Fig. 6

From: Isotope tracing reveals distinct substrate preference in murine melanoma subtypes with differing anti-tumor immunity

Fig. 6

Amino acid transporters and metabolic enzymes are associated with beneficial outcomes in melanoma patients. Z scores of survival effect due to mRNA expression of amino acid metabolic enzymes (A) and transporters (B) in melanoma patients from PRECOG database. C Clustering heatmap of amino acid transporter and metabolic enzyme gene expression in 159 melanoma patients from TCGA database. The results shown here are entirely or partly based upon data generated by the TCGA Research Network: https://www.cancer.gov/tcga. D Correlation coefficient (r value) of leukocyte infiltration to amino acid metabolic enzymes and transporter mRNA expression levels in TCGA melanoma patients. P< 0.05. E Correlation coefficient (r value) of cytolytic activity to amino acid metabolic enzymes and transporter expression levels in TCGA melanoma patients. P< 0.05

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Cancer & Metabolism

ISSN: 2049-3002