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Fig. 1 | Cancer & Metabolism

Fig. 1

From: Blocking lncRNA-SNHG16 sensitizes gastric cancer cells to 5-Fu through targeting the miR-506-3p-PTBP1-mediated glucose metabolism

Fig. 1

SNHG16 and PTBP1 are positively associated with gastric cancer. a SNHG16 expressions were detected in gastric tumors (n=55) and their matched normal gastric tissues by qRT-PCR. b Kaplan-Meier Plotter analyzes the survival rates of GC patients with high or low SNHG16 expressions. c Expressions of SNHG16 were detected in one non-tumorigenic gastric epithelial cell line, GES-1, and five GC cell lines by qRT-PCR. d PTBP1 expressions were detected in gastric tumors (n=55) and their matched normal gastric tissues by qRT-PCR and e IHC. f Kaplan-Meier Plotter analyzes the survival rates of GC patients with high or low PTBP1 expressions. g Expressions of PTBP1 were detected in one non-tumorigenic gastric epithelial cell line, GES-1, and five GC cell lines by qRT-PCR. h Pearson coefficient analysis shows a significantly positive correlation between SNHG16 and PTBP1 in gastric tumors. i AGS and SGC-7901 cells were transfected with control or SNHG16 siRNA, and protein expressions of PTBP1 were examined by Western blot. Data were presented as mean±S.D. *p<0.05; **p<0.01; ***p<0.001

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Cancer & Metabolism

ISSN: 2049-3002