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Fig. 1 | Cancer & Metabolism

Fig. 1

From: 13C tracer analysis suggests extensive recycling of endogenous CO2 in vivo

Fig. 1

Distinct 13C labeling of TCA intermediates with [U-13C]-glutamine is observed in in vitro cell cultures and in tumors in vivo. A Schematic of in vivo and in vitro tracing analysis. B 13C labeling patterns of metabolites from sarcoma cells (in vitro) fed with [U-13C]-glutamine medium for 3 h (h) and sarcoma tissue from sarcoma-bearing mice (in vivo) receiving [U-13C]-glutamine infusion for 3 h. Data are presented as mean ± SD n = 5 for animals and n = 3 for cultured cells. Data in this figure was after natural abundance correction

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