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Fig. 6 | Cancer & Metabolism

Fig. 6

From: Novel humanized monoclonal antibodies for targeting hypoxic human tumors via two distinct extracellular domains of carbonic anhydrase IX

Fig. 6

A Analysis of multicellular aggregation of C33-a CA IX with humanized antibody CA9hu-1 (HC4LC4) and CA9hu-2 (HC4LC5) after 24 h and 72 h on poly-HEMA-coated dishes. C33-a CA IX cells incubated in the absence of humanized antibody are marked as “negative control.” B Analysis of C33-a CA IX cells by propidium iodide staining and flow cytometry after 72 h of treatment with humanized CA9hu-1 (HC4LC4) and CA9hu-2 (HC4LC5) antibody. C33-a CA IX cells incubated in the absence of humanized antibody are marked as “ctrl”

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