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Fig. 4 | Cancer & Metabolism

Fig. 4

From: 3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation

Fig. 4

Changes in the levels of glutathione and nicotinamide dinucleotide. Changes in (A) glutathione and (B) nicotinamide dinucleotide (NADH) over time following addition of 100 μM 3BP. Measurements from independent samples were taken for each time point (n = 6). Metabolite levels are presented as abundance normalized to untreated control for each cell type and represent intracellular levels. The error bars represent the standard deviation from the mean. *P < 0.05, **P < 0.01, ***P < 0.001. Statistical significance was calculated using two-way ANOVA, corrected for multiple comparisons by the Tukey test. The multiplicity adjusted P value is presented

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