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Fig. 3 | Cancer & Metabolism

Fig. 3

From: Robust metabolic transcriptional components in 34,494 patient-derived cancer-related samples and cell lines

Fig. 3

Clustering activity scores of mTCs reveal multiple metabolic subtypes. A A total of 21,592 GEO samples were hierarchically clustered based on the activity scores of mTCs and divided into 67 metabolic subtypes. B A total of 10,817 TCGA samples were hierarchically clustered based on the mTC activity scores and divided into 58 metabolic subtypes. C Metabolic landscape of the subset of breast tissue samples in the GEO dataset. Subtypes with DFS data that were selected for survival analysis are highlighted. Gray labels designate the tissue types that are present in other datasets but are not present in the given dataset. D Distant relapse-free survival of breast cancer patients in the GEO dataset. Patient-derived samples were stratified per metabolic subtype. Kaplan-Meier curves are shown with a confidence interval of 0.95

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Cancer & Metabolism

ISSN: 2049-3002