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Fig. 2 | Cancer & Metabolism

Fig. 2

From: Robust metabolic transcriptional components in 34,494 patient-derived cancer-related samples and cell lines

Fig. 2

Metabolic TCs identify new genes potentially involved in metabolic processes. A, B Scatterplots showing the highest metabolic gene set enrichment score for every GEO (A) and TCGA (B) mTC (x-axis) versus the percentage of metabolically annotated genes among the top genes (genes with absolute weight > 3) in those mTCs. The size of the dots corresponds to the absolute amount of metabolically annotated genes in the corresponding mTC. The transparency of the dots is the same for all data points. Darker dot colors therefore mean that multiple data points are overlapping. C, D Top genes in GEO mTC 54 and TCGA mTC 127. Text colored white shows the genes that are a member of at least one of the 608 defined metabolic gene sets. Lines signify the genes that are the top genes in both GEO and TCGA mTCs. E, F Top genes in GEO mTC 11 and TCGA mTC 141

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