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Table 1 Pathway analysis of differential metabolites from global metabolomics

From: Integration of global metabolomics and lipidomics approaches reveals the molecular mechanisms and the potential biomarkers for postoperative recurrence in early-stage cholangiocarcinoma

Pathways Hits Raw p Holm adjust FDR Impact
Pyruvate metabolism 1 0.047 0.901 0.083 0.207
Alanine, aspartate and glutamate metabolism 4 0.029 0.668 0.083 0.197
Citrate cycle (TCA cycle) 3 0.016 0.389 0.083 0.169
Arginine and proline metabolism 5 0.043 0.901 0.083 0.156
Glycolysis/gluconeogenesis 1 0.047 0.901 0.083 0.100
Glycine, serine, and threonine metabolism 4 0.044 0.901 0.083 0.093
Glyoxylate and dicarboxylate metabolism 4 0.022 0.524 0.083 0.032
Propanoate metabolism 1 0.032 0.711 0.083 0
Cysteine and methionine metabolism 1 0.047 0.901 0.083 0
Tyrosine metabolism 1 0.047 0.901 0.083 0
Butanoate metabolism 2 0.050 0.901 0.083 0
  1. Hits matched metabolites in the pathway, raw p original p value calculated from enrichment analysis, Holm adjust adjust p value from Bonferroni method, FDR false discovery rate, Impact pathway impact calculated from topology analysis