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Fig. 4 | Cancer & Metabolism

Fig. 4

From: Integration of global metabolomics and lipidomics approaches reveals the molecular mechanisms and the potential biomarkers for postoperative recurrence in early-stage cholangiocarcinoma

Fig. 4

The summary of pathway analysis on differential metabolites between recurrence and non-recurrence, analyzed using MetaboAnalyst 4.0. A Metabolism pathway analysis from global metabolomics. B Metabolism pathway analysis from lipidomics. The color of the circle represents the p value, and the size of the circle represents the pathway impact. C The schematic diagram of metabolic pathways involved in CCA recurrence with red arrows indicating the most relevant pathway for recurrence. FAO fatty acid oxidation, CSC cancer stem cell, TG triacylglycerol, NEAAs non-essential amino acids, CD36 cluster of differentiation 36, ACLY ATP citrate lyase, SCD1 stearoyl-CoA desaturase-1

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