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Fig. 1 | Cancer & Metabolism

Fig. 1

From: The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer

Fig. 1

Typical immunohistochemical images of normal lung tissue showing weak expression of ARG2 and ASS1 by bronchial cells (indicated by arrows in a and b, respectively) and of lung cancer tissues (cf). c A squamous lung cancer with strong ARG2 expression, while image d shows extensive expression of ARG2 in the tumor stroma. e, f A squamous cell cancer and adenocarcinoma, respectively, with strong expression of ASS1 by cancer cells (arrows). The thick arrow in c shows intense lymphocytic infiltration of the tumor stroma negative for ASS1

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