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Fig. 3 | Cancer & Metabolism

Fig. 3

From: Pyruvate carboxylase and cancer progression

Fig. 3

Regulation of PC in cancer cells. Several factors have been identified which modify PC transcriptional activation, transcript levels, and protein levels specifically in cancer cells. Further elucidation of PC regulators in the context of cancer may be useful in identifying strategies to inhibit PC and block cancer progression. 1,25(OH)2D—1,25-dihydroxyvitamin D; GCASPC lncRNA—gallbladder cancer-associated suppressor of pyruvate carboxylase long noncoding RNA; VDR—vitamin D receptor

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