| |
Low-grade
|
High-grade
|
Pa
|
Pb
|
|---|
|
mRNA expression (× 100)
|
(N = 116)
|
(N = 84)
|
|---|
| |
Frozen tissue
| | | |
|
FOXC2
|
14.360 ± 29.842
|
9.820 ± 19.779
|
0.226
|
0.855
|
|
CLIP4
|
10.332 ± 15.012
|
17.307 ± 33.837
|
0.080
|
0.911
|
|
PBRM1
|
7.592 ± 8.283
|
8.543 ± 12.242
|
0.538
|
0.391
|
|
SETD2
|
2.615 ± 2.606
|
0.619 ± 0.633
|
< 0.001
|
0.095
|
|
BAP1
|
3.074 ± 12.171
|
19.778 ± 64.299
|
0.021
|
0.831
|
|
KDM5C
|
1.911 ± 4.806
|
1.763 ± 2.970
|
0.803
|
0.553
|
|
AQP1
|
2.337 ± 1.052
|
0.631 ± 0.903
|
< 0.001
|
0.117
|
|
DDX11
|
1.177 ± 2.103
|
12.763 ± 9.870
|
< 0.001
|
< 0.001
|
|
BAIAP2L1
|
3.155 ± 4.468
|
2.084 ± 2.931
|
0.042
|
0.448
|
|
TMEM38B
|
6.567 ± 12.125
|
4.838 ± 7.751
|
0.221
|
0.511
|
| |
Plasma
| | | |
|
FOXC2
|
16.649 ± 8.717
|
16.226 ± 11.721
|
0.770
|
0.490
|
|
CLIP4
|
16.241 ± 20.357
|
18.619 ± 24.948
|
0.460
|
0.333
|
|
PBRM1
|
5.672 ± 38.886
|
2.065 ± 1.880
|
0.397
|
0.538
|
|
SETD2
|
2.736 ± 1.488
|
0.610 ± 0.771
|
< 0.001
|
0.269
|
|
BAP1
|
26.289 ± 146.051
|
132.993 ± 435.106
|
0.033
|
0.520
|
|
KDM5C
|
6.804 ± 8.069
|
14.961 ± 21.136
|
0.001
|
0.964
|
|
AQP1
|
8.376 ± 16.698
|
12.376 ± 19.408
|
0.129
|
0.965
|
|
DDX11
|
3.545 ± 7.810
|
4.778 ± 8.911
|
0.311
|
0.953
|
|
BAIAP2L1
|
5.098 ± 12.002
|
10.425 ± 16.291
|
0.012
|
0.827
|
|
TMEM38B
|
21.343 ± 30.192
|
17.099 ± 24.749
|
0.277
|
0.950
|
- Data are shown as the means ± standard deviations
- aP values determined using Student’s t test for univariate analysis
- bP values determined using logistic regression for multivariate analysis
