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Table 3 Expression of target genes in patients with clear-cell renal-cell carcinoma characterized by high/low visceral adiposity

From: Association between visceral adiposity and DDX11 as a predictor of aggressiveness of small clear-cell renal-cell carcinoma: a prospective clinical trial

 

Low visceral adiposity

High visceral adiposity

Pa

Pb

mRNA expression (× 100)

(N = 100)

(N = 100)

  
 

Frozen tissue

   

FOXC2

17.011 ± 33.556

7.896 ± 14.304

0.014

0.003

CLIP4

17.158 ± 32.455

9.365 ± 12.712

0.027

0.121

PBRM1

8.950 ± 11.257

7.032 ± 8.787

0.181

0.249

SETD2

1.476 ± 2.153

2.077 ± 2.316

0.059

0.759

BAP1

18.530 ± 59.910

1.649 ± 6.515

0.006

0.201

KDM5C

1.744 ± 2.704

1.954 ± 5.187

0.720

0.508

AQP1

1.283 ± 1.486

1.958 ± 0.981

< 0.001

0.008

DDX11

10.196 ± 10.477

1.890 ± 2.875

< 0.001

< 0.001

BAIAP2L1

3.007 ± 4.574

2.403 ± 3.139

0.277

0.051

TMEM38B

4.627 ± 7.711

7.055 ± 12.656

0.103

0.382

 

Plasma

   

FOXC2

16.708 ± 11.659

16.235 ± 8.215

0.740

0.705

CLIP4

16.848 ± 22.763

17.631 ± 22.080

0.805

0.895

PBRM1

2.452 ± 2.180

5.751 ± 41.896

0.417

0.099

SETD2

1.339 ± 1.690

2.346 ± 1.388

< 0.001

0.512

BAP1

98.325 ± 357.418

43.885 ± 244.658

0.210

0.633

KDM5C

13.468 ± 19.377

6.992 ± 9.286

0.003

0.776

AQP1

12.095 ± 19.380

8.017 ± 16.235

0.108

0.286

DDX11

5.484 ± 11.271

2.641 ± 2.657

0.016

0.081

BAIAP2L1

9.706 ± 15.835

4.965 ± 11.904

0.018

0.140

TMEM38B

17.087 ± 21.024

22.035 ± 33.570

0.213

0.523

  1. Data are shown as the means ± standard deviations
  2. aP values determined using Student’s t-test for univariate analysis
  3. bP values determined using logistic regression for multivariate analysis