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Table 2 Clinicopathological characteristics according to visceral adipose tissue content

From: Association between visceral adiposity and DDX11 as a predictor of aggressiveness of small clear-cell renal-cell carcinoma: a prospective clinical trial

  Q1 Q2 Q3 Q4 P
Median age (range) 57.5 (51.0–62.0) 60.0 (46.0–68.0) 46.0 (39.0–57.3) 51.0 (42.0–54.0) < 0.001
No. gender, n (%)      
Male 24 (48.0%) 33 (66.0%) 46 (92.0%) 50 (100.0%) < 0.001
Female 26 (52.0%) 17 (34.0%) 4 (8.0%) 0 (0.0%)
Median tumor size (cm) (range) 1.8 (1.2–2.8) 2.5 (1.8–3.6) 1.6 (1.4–1.7) 2.1 (1.2–2.9) < 0.001
Median BMI (kg/m2) (range) 22.9 (21.9–24.6) 24.4 (23.0–26.6) 27.7 (24.1–29.0) 27.1 (25.1–29.2) < 0.001
No. comorbid conditions, n (%)      
Hypertension 13 (26.0%) 26 (52.0%) 9 (18.0%) 18 (36.0%) 0.002
Hypercholesterolemia 0 (0.0%) 4 (8.0%) 4 (8.0%) 8 (16.0%) 0.034
Diabetes 8 (16.0%) 3 (6.0%) 6 (12.0%) 3 (6.0%) 0.261
No. smoking status, n (%)      < 0.001
Never 35 (70.0%) 22 (44.0%) 12 (24.0%) 6 (12.0%)
Former 12 (24.0%) 22 (44.0%) 22 (44.0%) 14 (28.0%)
Current 3 (6.0%) 6 (12.0%) 16 (32.0%) 30 (60.0%)
No. alcohol status, n (%)      
Never 28 (56.0%) 20 (40.0%) 15 (30.0%) 6 (12.0%) < 0.001
Former 7 (14.0%) 6 (12.0%) 9 (18.0%) 18 (36.0%)
Current 15 (30.0%) 24 (48.0%) 26 (52.0%) 26 (52.0%)
No. ISUP grade, n (%)      
Low-grade (1–2) 10 (20.0%) 20 (40.0%) 46 (92.0%) 40 (80.0%) < 0.001
High-grade (3–4) 40 (80.0%) 30 (60.0%) 4 (8.0%) 10 (20.0%)
  1. Data are presented as medians (interquartile ranges) for continuous variables and as percentage for categorical variables. P values from one-way analysis of variance and chi-square test or Fisher’s exact test were used to determine mean differences for continuous and categorical variables, respectively, based on VAT quartiles. BMI body mass index, SAT subcutaneous adipose tissue, TAT total adipose tissue, VAT visceral adipose tissue, VAT% percentage of visceral adipose tissue