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Fig. 5 | Cancer & Metabolism

Fig. 5

From: Sulfasalazine modifies metabolic profiles and enhances cisplatin chemosensitivity on cholangiocarcinoma cells in in vitro and in vivo models

Fig. 5

OPLS-DA analysis distinguished metabolites between control and treatment with cisplatin, or sulfasalazine, or a combination of both. a OPLS-DA analysis shows that the cross-validation plot and coefficient loading plots derived from 1 H NMR spectra of control and treatment samples were altered in the control and cisplatin models, b control and sulfasalazine, and c control and cisplatin plus sulfasalazine. The upper section (above 0) of the loadings plot characterizes metabolites higher for the control, whereas the lower section (below 0) represents metabolites that are higher for the treatment groups. The color of each peak relates to the correlation value of the metabolites in the discrimination model

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Cancer & Metabolism

ISSN: 2049-3002