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Fig. 2 | Cancer & Metabolism

Fig. 2

From: Sulfasalazine modifies metabolic profiles and enhances cisplatin chemosensitivity on cholangiocarcinoma cells in in vitro and in vivo models

Fig. 2

SSZ inhibits cell growth and activates cell death in the in vivo model. a Time line of nude mice treatment with cisplatin in the absence/present of sulfasalazine. b The tumor mass after treatment. c The tumor volume expressed as the mean ± standard deviation of 10 tumor masses in 5 nude mice in each group. d The tumor weight expressed as the mean ± standard deviation of 10 tumor masses in 5 nude mice in each group. e The proliferation index indicated by Ki67 staining-positive cells, and the percentage represented as the mean±standard deviation of 5 nude mice in each group. f Apoptosis was measured by TUNEL assay and the percentage is presented as the mean±standard deviation of 5 nude mice in each group

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