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Fig. 3 | Cancer & Metabolism

Fig. 3

From: Prognostic value of metabolic tumor volume and total lesion glycolysis on preoperative 18F-FDG PET/CT in patients with localized primary gastrointestinal stromal tumors

Fig. 3

Representative cases. Patients with malignant gastrointestinal stromal tumors (GISTs) of similar size and mitotic count but different total lesion glycolysis (TLG) values and prognosis. a–d A 65-year-old woman with gastric GIST (size 13 cm, > 10/50 per high-power field (HPF) mitotic count, high-risk National Institutes of Health [NIH] criteria). The maximum standard uptake value (SUVmax) was 12.99, metabolic tumor volume (MTV) was 699.64 cm3, and TLG was 4350.31 g. Tumor recurrence was noted at 30.6 months after surgery. e–h A 68-year-old woman with gastric GIST (size 12.3 cm, > 10/50 per HPFs mitotic count, high-risk NIH criteria). SUVmax 4.62, MTV 76.75 cm3, TLG 221.67 g. This patient had no evidence of recurrence (42.7 months of follow-up after surgery). a, e 18F-Fluorodeoxyglucose positron emission tomography (18F-FDG PET) maximum intensity projection. b, f Coronal fusion 18F-FDG PET/computed tomography (CT). c, g Transaxial fusion 18F-PET/CT. d, h Transaxial contrast-enhanced CT. Intensity of 18F-FDG uptake in fusion images b and c were adjusted to show intratumoral inhomogeneous uptake

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Cancer & Metabolism

ISSN: 2049-3002