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Fig. 2 | Cancer & Metabolism

Fig. 2

From: RNF115 promotes lung adenocarcinoma through Wnt/β-catenin pathway activation by mediating APC ubiquitination

Fig. 2

Effectiveness of RNF115 expression on proliferation and apoptosis in LUAD cells. ae Comparison of RNF115 expression, cellular proliferation, and apoptosis between H358 or H1975 cells transfected with shRNF115 (1# and 2#) and control shRNA (NC). a Expression of RNF115 protein by western blotting with the loading control as GAPDH. b, c Measurement of cell proliferation by CCK-8 assay (b) and Click-iT EdU Cell Proliferation Assay (c). d The ratio of apoptotic cells. ***P < 0.001 vs NC. e Expression of PCNA and Cleaved caspase-3 by western blotting. fi Comparison of RNF115 expression, cellular proliferation, and apoptosis between H1299 cells transfected with oeRNF115 and Vector control. f Expression of RNF115 protein by western blotting with the loading control as GAPDH. g, h Measurement of cell proliferation by CCK-8 assay (g) and Click-iT EdU Cell Proliferation Assay (h). i The ratio of apoptotic cells. **P < 0.01 and ***P < 0.001 vs Vector

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