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Fig. 1 | Cancer & Metabolism

Fig. 1

From: Metabolic regulation of calcium pumps in pancreatic cancer: role of phosphofructokinase-fructose-bisphosphatase-3 (PFKFB3)

Fig. 1

Expression of PFKFB3 is upregulated and correlates with poor prognosis in PDAC: a Heat map analysis of overexpression of PFKFB isoforms 1–4 and PFKP in tumour tissue versus healthy pancreatic tissue in the pancreas resected from PDAC patients (datamined from Badea Pancreas dataset using Oncomine [35]) b Box and whisker plot displaying PFKFB3 expression in tumour tissue versus healthy tissue from resected tissue (unpaired t test; n = 39). c Survival rates of PDAC patients with high or low expression of PFKFB3 estimated using the Kaplan–Meier method and proportional hazards analysis; n = 51, p = 0.003 (figure generated using PROGgeneV2, ****p < 0.0005)

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