Skip to main content

Table 1 Characteristics of the volunteers participating and the dosages of 5-13C-glutamine infused and their pre- and post-blood plasma urea nitrogen (BUN) and ammonia levels

From: In vivo assessment of glutamine anaplerosis into the TCA cycle in human pre-malignant and malignant clonal plasma cells

Pt #

Age

Sex

Glutamine dose

BUN (mg/dL)

NH3 (μmol/L)

Prime dose

Infusion dose

Pre

Post

Pre

Post

1a

35

F

3 mg/kg

3 mg/kg

15

14

< 10

15

2a

24

M

3 mg/kg

3 mg/kg

20

15

12

< 10

3a

27

F

3 mg/kg

3 mg/kg

16

16

< 10

< 10

4a

29

M

3 mg/kg

3 mg/kg

12

12

15

18

5

24

M

3.5 mg/kg

3.5 mg/kg

16

15

< 10

< 10

6

29

F

4 mg/kg

4 mg/kg

19

13

< 10

24

7

52

F

4 mg/kg

4 mg/kg

9

13

< 10

19

  1. aThe participants whose non-malignant plasma cells from the marrow were unable to undergo isotopomer assessments by GC-MS due to technical complications