Table 3 Association of tumor characteristics and baseline LDL receptor expression

Age years (median)

62

67

67

0.44

Tumor size mm (median)

20

22

25

0.43

Tumor grade (NHG)

0.28

 I

2

1

3

 II

4

2

3

 III

5

4

2

Mitotic index

0.33

 1

6

1

6

 2

0

2

1

 3

5

3

1

ER (n = 31)

0.25

 Positive

9

7

8

 Negative

2

0

0

PR (n = 31)

0.27

 Positive

9

5

7

 Negative

2

2

1

HER2 (n = 30)

0.56

 0

3

1

2

 1+

3

1

4

 2+

2

4

1

 3+

3

1

1

Ki67 index (n = 26)

0.22

 Low

5

3

6

 High

6

2

2

HMGCR (n = 38)

0.25

 Negative

7

2

2

 Positive

4

4

6

Serum lipid levels (median)

 LDL pre-treatment

3.74

3.45

3.8

0.84

 HDL pre-treatment

1.6

1.73

1.6

0.26

 Cholesterol pre-treatment

6.2

5.55

6.1

0.67

 Apolipoprotein B pre-treatment

1.01

0.95

1.17

0.22

 Apolipoprotein A1 pre-treatment

1.78

1.66

1.58

0.06

 LDL post-treatment

1.48

1.7

1.8

0.99

 HDL post-treatment

1.63

1.64

1.5

0.41

 Cholesterol post-treatment

4.1

3.5

3.4

0.43

 Apolipoprotein B post-treatment

0.54

0.56

0.66

0.43

 Apolipoprotein A1 post-treatment

1.71

1.51

1.54

0.19