Skip to main content
Fig. 6 | Cancer & Metabolism

Fig. 6

From: The conversion of formate into purines stimulates mTORC1 leading to CAD-dependent activation of pyrimidine synthesis

Fig. 6

Levels of pyrimidines and purines at 24 h. a–i Peak areas of the reported metabolites in HAP1-ΔSHMT2 cells supplemented with different concentrations of formate, without or with rapamycin treatment. Quantifications are done relative to the Taurine peak area. Bars represent the mean and error bars the standard deviation from 3 independent experiments, each represented by the symbols. The p values shown were obtained using a t test with two tails and unequal variance

Back to article page