Fig. 5
From: PHGDH supports liver ceramide synthesis and sustains lipid homeostasis
PHGDH knockdown depletes ceramides. a Concentration of individual ceramides in the serum of 8-month-old shREN (N = 12) and shPHGDH mice (N = 11). b Quantity of individual ceramides in the liver of 8-month-old shREN (N = 11) and shPHGDH (N = 12) mice. Quantities were normalized to mg of tissue. c Liver serine quantities of 8-month-old shREN (N = 11) and shPHGDH (N = 11) mice. Quantities were normalized to mg of tissue