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Fig. 5 | Cancer & Metabolism

Fig. 5

From: A yeast phenomic model for the influence of Warburg metabolism on genetic buffering of doxorubicin

Fig. 5

Respiration increases the role for chromatin organization in buffering doxorubicin toxicity. a GO term-specific heatmaps for chromatin organization and its child terms (indicated by arrows) clarify related but distinct biological functions that buffer doxorubicin, with respect to Warburg status. b, c L-based doxorubicin-gene interaction scores associated with GO terms that were enriched in cluster 2-0.7-2. Dashed lines indicate z-score thresholds for enhancers (> 2) and suppressors (≤ 2). Sub-threshold gene interaction values are plotted, but not labeled

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