Fig. 4

GO annotations associated with deletion enhancement or suppression of doxorubicin cytotoxicity, with respect to Warburg-dependence. Representative GO terms are listed, which were identified by REMc/GTF (orange), GTA (purple), or both methods, for HLD (left, red), HLEG (right, blue), or both media types (black), and for enhancement (above dashed line) or suppression (below dashed line) of doxorubicin cytotoxicity. Distance above or below the horizontal dashed line indicates the GTA value for terms identified by REMc or the GTA score if identified by GTA (see the “Methods” section). See Additional files 5 and 6, respectively, for all REMc and GTA results