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Fig. 1 | Cancer & Metabolism

Fig. 1

From: CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism

Fig. 1

CHCHD4 expression positively correlates with OXPHOS and proliferative pathways in tumours. a Chart shows GSEA of genes positively correlated with CHCHD4 expression in Novartis/Broad Institute Cancer Cell Line Encyclopedia RNASeq data. n = 967 cell lines. b, c Charts show GSEA of genes positively correlated with CHCHD4 expression in colon adenocarcinoma (b) and breast cancer (c) patient tumours. d Heatmap of selected genes from the HALLMARK_OXIDATIVE_PHOSPHORYLATION gene-set (Broad Institute) that are positively correlated with CHCHD4 expression in colon adenocarcinoma patient tumours. e, f Heatmap of selected genes from the HALLMARK_MTORC1_SIGNALLING gene-set (Broad Institute) that are positively correlated with CHCHD4 expression in colon adenocarcinoma (e) and breast cancer (f) patient tumours

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